COMPUTATIONAL STUDIES ON SEARCHING POTENTIAL PHYTOCHEMICALS AGAINST DNA POLYMERASE ACTIVITY OF THE MONKEYPOX VIRUS

Computational studies on searching potential phytochemicals against DNA polymerase activity of the monkeypox virus

Objectives: The outbreak of monkeypox virus (MPXV) is an emerging epidemic of medical concern with 65353 confirmed cases of infection and a Books fatality of 115 worldwide.Since May 2022, MPXV has been rapidly disseminating across the globe through various modes of transmission, including direct contact, respiratory droplets, and consensual sex.Bec

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Pharmacokinetic study of Tangwang Mingmu granule for the management of diabetic retinopathy based on network pharmacology

Context Tangwang Mingmu granule (TWMM), a traditional Chinese medicine, has been widely used in the treatment of diabetic retinopathy (DR), the most common microvascular complication in diabetes mellitus.Objective To establish a method to select target compounds from herbs for a pharmacokinetic study using network pharmacology, which could be appli

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